CD19 B Cells PE 100TESTS

Code: MAB1794H D2-231

Application

Detect CD19 using this Anti-Human B cells (CD19) Antibody, clone FMC63, Phycoerythrin conjugated validated for use in FC.

This antibody is useful for enumer...


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€388.00 EACH
€477.24 inc. VAT

Application

Detect CD19 using this Anti-Human B cells (CD19) Antibody, clone FMC63, Phycoerythrin conjugated validated for use in FC.

This antibody is useful for enumerating normal B lymphocytes and typing B cell malignancies by flow cytometry.

SUGGESTED USAGE

Flow cytometry - use 10 µl direct from the vial per 100 µl of whole blood, or 1 x 10E(6) peripheral blood mononuclear cells (PBMC) in 100 µl buffer.

Research Sub CategoryImmunoglobulins & Immunology

Research CategoryInflammation & Immunology

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

General description

BIOCHEMISTRY:

p I = 7.0

Immunogen

Raji cells

Legal Information

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

Linkage

Replaces: CBL141P

Physical form

Purified from mouse ascitic fluid. R-Phycoerythrin conjugated. The antibody is supplied in 1.0ml phosphate buffered saline, pH 7.4, containing 0.2% bovine serum albumin and 0.1% sodium azide. The characteristics of each lot are tested by electrophoresis and flow cytometry.

Specificity

This specificity of this antibody is equivalent to that of CD19 monoclonal antibodies (Zola et al., 1988, 1989), based on comparative studies, antigen recognition and positive reaction with a CD19 transfected cell line. It detects a 96 kD single chain glycoprotein on the surface of human B lineage cells, including pre-B cells. B cells can be detected in peripheral blood and tissues. The antibody reacts with most B cell malignancies including chronic lymphocytic leukemia and most lymphomas, but not multiple myeloma.

Cell reactivity:

Normal:Stains all B lymphocytes in peripheral blood and spleen. Negative on granulocytes, monocytes, platelets, erythrocytes and T lymphocytes.

Clinical:

B cell chronic lymphocytic leukemia (B-CLL) +

Pro lymphocytic leukemia (PLL +

Hairy cell leukemia (HCL) +

Common acute lymphoblastic leukemia (CALL) +

Pre-B acute lymphoblastic leukemia (pre-B-ALL) +

NULL-acute lymphoblastic leukemia (NULL-ALL) +

T-acute lymphoblastic leukemia (T-ALL) -

T-common lymphocytic leukemia (T-CLL -

Storage and Stability

Store at 2 to 8°C, for up to 6 months. DO NOT FREEZE. Protect from light.

WARNING: The monoclonal reagent solution contains 0.1% sodium azide as a preservative. Due to potential hazards arising from the build up of this material in pipes, spent reagent should be disposed of with liberal volumes of water.

antibody formpurified antibody
antibody product typeprimary antibodies
biological sourcemouse
cloneFMC63, monoclonal
conjugatePE
Gene Informationhuman ... CD19(930)
isotypeIgG2a
manufacturer/tradenameChemicon®
NCBI accession no.NM_001770.4
Quality Level100
shipped inwet ice
species reactivityhuman
technique(s)flow cytometry: suitable
UniProt accession no.P15391
This product has met the following criteria to qualify for the following awards:



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